BRIAN CHEN LAB

Neural Circuit Formation

PUBLICATIONS

Vieira Dos Santos, J., Yu, R.Y., Terceros, A., Chen, B.E.  2019. FGF receptors are required for proper axonal branch targeting in Drosophila. 
Molecular Brain 12: 84.  Abstract
Lo, C.A., Chen, B.E.  2019.  Parental Allele-Specific Protein Expression in Single Cells In Vivo. 
Developmental Biology  454: 66-73. Abstract 
BioTechniques cover with three flasks
Kays, I., Chen, B.E.  2019.  Protein and RNA Quantification of Multiple Genes in Single Cells. BioTechniques  66: 15–21.  Abstract.
PDF icon Protein and RNA Quantification
Suciu, R. M., Aydin, E., Chen, B. E. 2015. GeneDig: a web application for accessing genomic and bioinformatics knowledge. BMC Bioinformatics 16: 67.  Abstract
PDF icon GeneDig Web Application
brain image
Schmucker, D, Chen, B. 2009. Dscam and DSCAM: Complex genes in simple animals, complex animals yet simple genes. Genes & Development 23: 147-156.  Abstract
PDF icon Complex genes in simple animals
Lo, C.A., Greben, A.W., Chen, B. E.  2017. Generating stable cell lines with quantifiable protein production using CRISPR/Cas9-mediated knock-in. BioTechniques 62: 165-174.  Abstract
PDF icon Generating stable cell lines
Lo, C.*, Kays, I.*, Emran, F., Lin, T., Cvetkovska, V., Chen, B. E. 2015. Quantification of Protein Levels in Single Living Cells. Cell Reports 13: 2634-2644.  Abstract
PDF icon Quantification of Protein Levels in Single Living Cells
Lo, C.*, Kays, I.*, Emran, F., Lin, T., Cvetkovska, V., Chen, B. E. 2015. Quantification of Protein Levels in Single Living Cells. Cell Reports 13: 2634-2644.  Abstract
PDF icon Quantification of Protein Levels in Single Living Cells
Chen, B. E., Lendvai, B., Nimchinsky, E. A., Burbach, B., Fox, K., Svoboda, K. 2000. Imaging high-resolution structure of GFP-expressing neurons in the neocortex in vivo.  Learn. Mem. 7: 433-41. Abstract
PDF icon Imaging high-resolution structure of GFP
Chen, B. E., Trachtenberg, J. T., Holtmaat, A. J., Svoboda, K. Long-term, high-resolution imaging in the neocortex in vivo. 2004. In Live Cell Imaging: A Laboratory Manual. (ed. Goldman R., Spector, D.) Cold Spring Harbor Laboratory, NY:
Cold Spring Harbor Laboratory Press. Abstract
Kays, I.*, Cvetkovska, V.*, Chen, B. E. 2014. Structural and functional analysis of single neurons to correlate synaptic connectivity with grooming behavior. Nature Protocols 9: 1-10.  Abstract Our protocol was featured on the cover of the January 2014 issue of Nature Protocols.
PDF icon Structural and functional analysis of single neurons
Lendvai, B., Stern, E. A., Chen, B., Svoboda, K. 2000. Experience-dependent plasticity of dendritic spines in the developing rat barrel cortex in vivo. Nature 404: 876-881.  Abstract This paper was highlighted by Nature in a News and View by Kevin Fox (2000, 404: 825-827).
PDF icon Experience-Dependent Plasticity of Dendritic Spines
Chen, B. E.* , Kondo, M.*, Garnier, A., Watson, F.L., Püttmann-Holgado, R., Lamar, D.R., Schmucker, D. 2006. The molecular diversity of Dscam is functionally required for neuronal wiring specificity in Drosophila. Cell 125: 607-620.  Abstract This paper was highlighted by Cell in a Preview by Bharadwaj and Kolodkin (2006, 125: 421-424),  and has earned a Faculty of 1000 Factor of 6.5 Must Read.
PDF icon The Molecular Diversity of Dscam
Cvetkovska, V.*, Hibbert, A. D.*, Emran, F., Chen, B. E. 2013. Overexpression of Down Syndrome Cell Adhesion Molecule impairs precise synaptic targeting. Nature Neuroscience 16: 677-682.  Abstract This paper was highlighted by Nature Reviews Neuroscience in a Research Highlight (2013, 14: 458–459), a YouTube video produced by SimpliSci, and has earned a Faculty of 1000 Factor of 2.0.
PDF icon Overexpression of Down Syndrome Cell Adhesion Molecule
Cvetkovska, V.*, Hibbert, A. D.*, Emran, F., Chen, B. E. 2013. Overexpression of Down Syndrome Cell Adhesion Molecule impairs precise synaptic targeting. Nature Neuroscience 16: 677-682.  Abstract This paper was highlighted by Nature Reviews Neuroscience in a Research Highlight (2013, 14: 458–459), a YouTube video produced by SimpliSci, and has earned a Faculty of 1000 Factor of 2.0.
PDF icon Overexpression of Down Syndrome Cell Adhesion Molecule
Trachtenberg, J. T.*, Chen, B. E.*, Knott, G. W., Feng, G., Sanes, J. R., Welker, E., Svoboda, K. 2002. Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex. Nature 420: 788-794.  Abstract This paper was highlighted by Nature in a News and Views by Ottersen and Helm (2002, 420: 751-752),  and also earned a Faculty of 1000 Factor of 8.0 Exceptional.
PDF icon Long-term in Vivo Imaging of Experience